AN2 Therapeutics shares fall after pausing lung illness examine enrollment – ET HealthWorld | Pharma

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New Delhi: AN2 Therapeutics stated on Monday it can pause additional enrollment in a late-stage examine testing its experimental lead drug on account of probably lower-than-expected efficacy, sending shares down 65 per cent premarket.

It stated the pause was not on account of any security considerations however due to an evaluation testing its drug on the mid stage of the examine.

The corporate was testing epetraborole, a once-daily oral drug, to probably deal with MAC lung disease which is brought on by a gaggle of micro organism known as mycobacterium avium complicated.

Greater than 86,000 People are affected by infectious illnesses brought on by these micro organism, in keeping with Cleveland Clinic. MAC lung illness is the commonest, making up almost 80 per cent of the infections.

AN2 has to date enrolled almost 100 sufferers for the examine. It had beforehand deliberate to enroll about 234 sufferers.

Sufferers already enrolled for the examine throughout September might be allowed to proceed, the corporate stated.

AN2 stated the choice to pause enrollment will give it time to additional consider the information. It expects to supply additional particulars on the examine within the second quarter of the yr.

The drug developer stated an impartial group of specialists will conduct an evaluation and advocate the following steps, which might embrace adjustments to the examine’s protocol.

  • Revealed On Feb 13, 2024 at 11:51 AM IST

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